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This anti-inflammatory mechanism helps protect β cells from inflammatory damage ( 4.1.4.2 Effects on the gut–adipose axis In terms of lipid metabolism, SBAs co-ordinately regulate lipid storage and consumption through FXR in different organs
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By contrast, PPT-type metabolites, with glycosylation at C-6 and C-20 positions, are often associated with antioxidant and anti-inflammatory activities, particularly in models of photoaging and inflammatory dermatoses (Wang et al., 2026)