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In Europe, the incidence is not currently known, but more than 90% of fatalities after mushroom ingestion have been attributed to death cap mushrooms (amatoxins) [24]

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To limit the number of false-positive doublets, which are common in snRNA-seq demultiplexing owing to background RNA and potential large duplications or deletions shared by tumours in the same cohort, we used the gnomADv4 exome data to subset only the most likely germline variants